Top 30 Healthtech Venture Capital Firms In The US [2022]

Whether you are raising seed, Series A or higher, in this article we have listed our top picks of the best venture capital firms for Healthtech & Medtech startups in the US.

So, if you haven’t yet started to reach out, here is a good place to start learning about them.

Note: this article is part of a series where we present you the top Venture Capital firms across the world. Have a look at the complete list here.

Top Venture Capital Firms For Healthcare Startups

Here’s a summary of our top 30 picks for the best venture capital firms for Healthtech startups in the US (in alphabetical order):

NameLocationSector focusInvestment stageInvestment rangeInvestments
Abundant Venture PartnersChicagoHealthtechSeed, Series AUndisclosed28
Advanced Technology VenturesMenlo Park (San Francisco Bay Area), BostonIT, CleanTech, HealthcareSeries A+Undisclosed250+
Bessemer Venture PartnersSan Francisco, Silicon Valley, Boston, New York City, Westchester, India, Israel, LondonConsumer, Enterprise, HealthcareSeed, Series AUndisclosed368
BioAdvancePhiladelphiaLife ScienceEarly Stage$500k to $1.5 million50+
Chrysalis VenturesLouisvilleHealthcare and TechnologySeries AN/A55
Delphi VenturesSan Mateo (San Francisco Bay Area)Life SciencesSeed to Series A+Undisclosed170
DreamitPhiladelphiaHealthTech, SecureTech, UrbanTechSeed Round$500,000300+
First Analysis Venture CapitalChicagoTech/SaaS, Healthcare, Environmental TechnologySeed, Series A$3M to $10M108
Fort VenturesFort WorthTech, Food, BiotechSeed, Series AN/A35
Green Park & Golf VenturesDallasMedical SciencesSeed, Series A$100k to $1M97
Illinois VenturesChicagoHealthcare, TechnologySeed to Series A+Undisclosed25
InnovaMemphisHealthtech, Bioscience, AgTechSeed, Series AUndisclosed100+
Keiretsu CapitalSeattleCleantech, Fintech, Healthtech, IT, ImpactSeedUndisclosed120+
Kleiner PerkinsMenlo Park (San Francisco Bay Area)Technology and Life SciencesSeed to Series A+Undisclosed335
Krillion VenturesMiamiHealthTech, PropTech, FinTechSeed, Series A$1M20+
MB Venture PartnersMemphisMedical Devices and BiotechSeed to Series A+Undisclosed41
Menlo VenturesSan Francisco, Menlo ParkConsumer, Enterprise, HealthcareSeed to Series A+Undisclosed160+
NEASan Francisco, Menlo Park, Timonium, New York, Chevy ChaseTechnology and HealthcareSeed to Series A+Undisclosed369
Norwest Venture PartnersSan Francisco, Palo Alto, India, IsraelConsumer, Enterprise, HealthcareSeed to Series A+$1M to $30M444
Providence VenturesSeattleHealthtech, MedtechSeed to Series A+Undisclosed26
PTV Healthcare CapitalAustinHealthcareSeries A+N/A17
Quaker PartnersPhiladelphiaHealthcareEarly StageUndisclosed (Currently Not Investing25
Rho VenturesNYCConsumer, Enterprise, Healthcare, CleantechSeed to Series A+Undisclosed243
Sandbox IndustriesChicagoHealthcare, Insurance, and SustainabilitySeed to Series A+Undisclosed83
SanteAustin, BostonBiotech, MedTech, HealthtechSeed, Series AN/A34
Silverton PartnersAustinConsumer, Enterprise, Fintech, HealthcareSeed, Series AN/A80+
SpringRock VenturesSeattleHealthtechSeed to Series A+$2M – $5M42
SV Health InvestorsBostonBiotech, Healthtech, MedtechSeed to Series A+Undisclosed170+
Texo VenturesAustinHealthcareSeries A+$3M – $10M12
Treehouse HoldingsAtlantaHealthtech & TechnologySeed, Series AUndisclosed4

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Texo Ventures

Location: Austin

Texo Ventures is an Austin-based venture capital firm that offers Series A+ investments to healthcare companies. It usually writes a check of anywhere between $3M and $10M.

Though they focus on healthtech companies, they target only those companies that are tech-enabled and require less capital for commercialization plus, have fewer regulatory hurdles and high scalability potential.

They also invest in companies working in the medical devices & diagnostics vertical, but select only those that are uniquely differentiated, and are in synergy with ongoing reform initiatives.

So far, Texo Ventures has invested in 12 healthcare companies including Sensentia, Caredox, BetterDoctor, Ortho Kinematics, OpenMarkets, and Alafair Biosciences.

PTV Healthcare Capital

Location: Austin

PTV Healthcare Capital is an Austin-based venture capital firm that focuses on companies working towards healthtech innovation. However, they prefer to work with those companies that bring disruptive medical technologies.

This venture capital firm offers Series A+ funding, but unfortunately, it does not disclose the exact investment amount anywhere on its website.

Apart from funds, PTV Healthcare Capital also provides critical expertise and business expansion resources to its portfolio companies.

So far, this venture capital firm has invested in 17 companies. Some of its portfolio companies include Apollo Endosurgery, Asuragen, Intersect ENT, Intuity Medical, Corventis, Cardiva Medical Inc., and BioForm Medical.

Quaker Partners

Location: Philadelphia

Quaker Partners is a venture capital firm that invests in companies in the healthcare sector. Usually, they invest in the early-stage healthcare startups, but they are open for investments in different stages. Unfortunately, Quaker Partners is currently not making new investments.

So far, Quaker Partners have invested in 25 high-impact and innovative healthcare companies in various verticals such as medical tools & devices, human diagnostics, healthcare services, biotechnology, and pharmaceuticals.

NYDHA, Rapid Micro Biosystems, TelaBio, and Vesper Medical are the current active portfolio companies of Quaker Partners.

Abundant Venture Partners

Location: Chicago

Chicago-based Abundant Venture Partners is a popular venture capital firm that focuses on startups in the Healthtech sector. This venture capital firm offers Seed and Series A funding to the selected companies.

Unfortunately, Abundant Venture Partners does not disclose the exact investment amount on its website. However, this venture capital firm connects its portfolio companies with its trusted partners to fuel growth. Apart from that, the VC firm also offers its deep operational expertise in the healthcare and related technology fields to help its portfolio companies.

So far, this VC firm has invested in 28 companies, some of which are Ardent.io, Avia, Cardinal Path, HealthFinch, Longbridge, and PatientWisdom, among others.

BioAdvance

Location: Philadelphia

BioAdvance is a VC firm that focuses on early-stage life science companies operating in the mid-Atlantic region. They actively invest in companies working in the fields of Health IT, Diagnostics, Research Tools, Medical Devices, and Therapeutics.

BioAdvance typically invests anywhere between $500k and $1.5M through a convertible note in 2 tranches. However, over the life of a company that they invest in, they may invest up to $5M.

It is important to note that they invest only in companies that work and operate in the mid-Atlantic region, which extends from New York City to Washington D.C.

Currently, they have 30 active portfolio companies.

SpringRock Ventures

Location: Seattle

Yet another Seattle-based venture capital firm, SpringRock Ventures offers Seed to Series A+ funding to companies operating in the healthcare sector with a focus on healthcare innovations spanning over SaaS, genomics, security, devices, services, general health, and oral health.

Though located in Seattle, SpringRock invests all across North America and their typical investment ranges between $2M and $5M per company. Apart from funding, this venture firm also extends help to the portfolio companies with deep industry expertise and constant support as co-founders.

So far, SpringRock has invested in 42 companies including Abett, Adolor, Bright.md, Cyrus Biotechnology, OverJet, Artemis, Bluebox, and more.

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Delphi Ventures

Location: San Mateo (San Francisco Bay Area)

Delphi Ventures is one of the first venture capital firms that was created with a focus on investing only in life sciences companies. Located in San Mateo in the San Francisco Bay Area, this venture capital firm has so far invested in 170 companies with 125 of them either reaching the IPO stage or went through M&A exits.

This venture capital firm offers Seed to Series A+ investments. However, it does not disclose the exact investment amount anywhere on its website. Some of the most notable recent investments made by Delphi Ventures include Salmedix, SeattleGenetics, Relypsa, OncoMed, Senseonics, Foresight Visions, and Karyopharm, among others.

Treehouse Holdings

Location: Atlanta

Yet another Atlanta-based venture capital firm, Treehouse Holdings is popular for investing in startups operational in the Healthtech and Technology segments. However, the firm doesn’t provide enough information on its website and never discloses the exact investment amount.

Treehouse Holdings offers Seed and Series A funds to the companies that it finds to have high-growth potential. This venture capital firm works together with its portfolio companies as a partner and helps them to grow big and turn into leading companies.

So far, Treehouse Holdings has invested in only four companies that are Code Runner, HumazeMD, ExamMed, and Laaser.

Green Park & Golf Ventures

Location: Dallas

With 60+ years of investment experience, Green Park & Golf Ventures has emerged as one of the finest venture capital firms in Dallas. This venture capital firm offers Seed to Series A funding for companies working in the medical sciences segment.

They typically write a check between $100k and $1M, but funding is not the only help they extend. In fact, they work along with their portfolio companies and provide valuable insights and connections that help them to grow rapidly.

This venture capital firm has made 97 first-time and 82 follow-on investments so far. Some of the major companies that the firm has funded include Adient, Empirical Science, Esculon, Socrates Health Solutions, and Ataia Medical, among others.

NEA

Location: San Francisco, Menlo Park, Timonium, New York, Chevy Chase

New Enterprise Associates or NEA is a popular venture capital firm with offices in San Francisco, Menlo Park, Timonium, New York, and Chevy Chase. NEA offers venture funding to companies operating in the Technology and Healthcare sectors. The firm offers Seed to Series A+ funding, but it does not disclose the exact investment amount anywhere on its website.

So far, NEA has invested in 369 companies including some popular names such as Patreon, MoneyTap, MasterClass, Coursera, Inkitt, Hyperion Therapeutics, Grid, DataBricks, Rapid Robotics, Upwork, Upstart, and Waymark, among others.

Apart from just offering funds, NEA also offers expert guidance and mentorship to every portfolio company throughout its lifecycle.

MB Venture Partners

Location: Memphis

MB Venture Partners is another famed venture capital firm operational in Memphis. They usually invest in companies working in the Medical Devices and Biotech sectors. However, MB Venture Partners has a special interest in product solutions trying to address musculoskeletal diseases.

This venture capital firm has deep experience in these fields and hence, offers guidance and proper mentorship to its portfolio companies. Unfortunately, the firm never discloses the exact investment amount anywhere on its site.

So far, MB Venture Partners has invested in 41 companies, some of which are Lineus Medical, EcoSurg, Hubble Telemedical, Compression Kinetics, Salient Surgical Technologies, and Expanding Orthopedics, among others.

Chrysalis Ventures

Location: Louisville

Louisville’s one of the top venture capital firms, Chrysalis Ventures known for offering Series A funding to technology and healthcare companies. The firm does not just offer to fund, but also offers active collaboration to help the portfolio companies achieve sustainable success.

Unfortunately, Chrysalis Ventures doesn’t disclose the exact investment amount anywhere on its website. However, they only select those companies for investment that show promise of high growth. Also, the companies applying for funding must be operating in the Midwest and Southeast.

So far, this venture capital firm has invested in 55 companies, some of which include big names like AT&T, TechRepublic, Rad Technologies, WebMD, Intechra, and Foundation Radiology Group, among others.

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Illinois Ventures

Location: Chicago

Headquartered in Chicago, Illinois Ventures is a famed venture capital firm that offers investment in Healthcare and Technology companies. This venture capital firm offers Seed to Series A+ funding to the selected companies.

However, it is important to note that this venture firm works with an entrepreneurial community of the University of Illinois and its alumni network. Just like many other venture capital firms, this firm also does not disclose the exact investment amount on its website.

So far, Illinois Venture has invested in 25 companies, some of which are Ouster, Inventables, Reconstruct, Skyryse, KeyWise AI, Natrion, and EarthSense, among others.

Providence Ventures

Location: Seattle

Seattle-based Providence Ventures is one of the most prominent venture capital firms that invest in medtech and healthtech companies. This venture firm offers Seed to Series A+ funding, but unfortunately, they do not disclose the exact investment amount on their website.

Apart from funding, the portfolio companies of Providence Ventures get access to the firm’s deep expertise and decision makes of the health system. This helps the portfolio companies in driving adoption and uncovering valuable insights about consumers.

So far, Providence Ventures has invested in 26 companies including big names like Bolder Surgical, Iris, Avia, Lyra, SpineZone, and more.

Kleiner Perkins

Location: Menlo Park (San Francisco Bay Area)

With 335 investments to date, Kleiner Perkins is one of the most prominent venture capital firms located in Menlo Park in the San Francisco Bay Area. This venture capital firm offers Seed to Series A+ funding to companies working in the Technology and Life Sciences sectors.

Unfortunately, Kleiner Perkins does not disclose the exact investment amount anywhere on its websites.

This venture capital firm has made investments in some of the most iconic companies of today’s world including names like Amazon, Twitter, Google, Spotify, AOL, Netscape, Slack, Sun Microsystems, Verisign, Airbnb, Audible, Compaq, Duolingo, Facebook, Groupon, Pinterest, and Uber, among others.

Advanced Technology Ventures

Location: Menlo Park (San Francisco Bay Area), Boston

One of the most famous VC firms in Menlo Park in the San Francisco Bay Area, Advanced Technology Ventures started operations in 1979. This venture capital firm also has a physical presence in Boston. Ever since its inception, the firm has invested in over 250 startups. Unfortunately, the venture capital firm does not disclose the investment amount.

Advanced Technology Ventures manages $1.8 billion in capital and focuses on startups working in disruptive technologies in cleantech, healthcare, and IT.

The firm offers Series A+ funding for those companies that can move forward to become sustainable and strong businesses.

Of the 250+ portfolio companies, 72 had successful exits so far. Some of the notable investments include Tripwire (sold to Belden), Cedexis (acquired by Cisco), and Actifo (sold to Google).

SV Health Investors

Location: Boston

SV Health Investors, as the name suggests, works with companies in the healthcare sector. To be more precise, they work with companies in Healthcare Growth, Biotech, Medtech, and Dementia verticals.

Operational for 27 years, the firm has invested in over 170 companies to date, some of which are based in the UK and the rest are in America. This venture capital firm offers Seed to Series A+ funding. However, they do not disclose the exact amount on their website.

Some of their most prominent portfolio companies include Adapt Health, Avitide, Caraway Therapeutics, CardioFocus, Healthify, Imbria Pharmaceuticals, etc.

Sante

Location: Austin, Boston

With physical offices in Austin and Boston, Sante is a popular venture capital firm that offers both Seed and Series A funding. This venture capital firm invests in HealthTech, MedTech, and Biotech companies.

Unfortunately, this venture capital firm does not disclose the exact investment amount anywhere on its website. Apart from providing funds, Sante offers its deep industry expertise and knowledge to its portfolio companies and helps them to succeed as sustainable and profitable businesses.

So far, the firm has invested in 34 companies, some of which are BaroLogics, CareHive, Claret Medical, Clairity, Endogenex, Geneos Therapeutics, Lumos Pharma, RapidPulse, and RiseHealth.

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Innova

Location: Memphis

Memphis-based Innova is yet another famous venture capital firm that is known for offering Seed and Series A investments to startups operating in the Healthcare, Technology, and AgTech sectors.

Innova never discloses the exact investment amount. However, this venture capital firm looks for companies that have high-growth potential and have strong IP or other competitive advantages over their competitors.

Apart from the funds, Innova also offers hands-on mentorship and experienced leadership to its portfolio companies.

So far, Innova has invested in 100+ companies, some of which are Advanced Catheter Therapies, Handminder, NCrease, Service Bot Software, AgriSync, and HerdDogg, among others.

Bessemer Venture Partners

Location: San Francisco, Silicon Valley, Boston, New York City, Westchester, India, Israel, London

Bessemer Venture Partners is one of the most famous venture capital firms in San Francisco. However, it also has a physical presence in Silicon Valley, Boston, New York City, Westchester, India, Israel, and London.

So far, this venture capital firm has invested in 368 companies globally. It offers Seed and Series A funding, but unfortunately, the firm does not disclose the exact investment amount anywhere on its website.

Bessemer Venture Partners offers investment to companies operating in three verticals – Consumer, Enterprise, and Healthcare. Pinterest, Shopify, LinkedIn, Twitch, Yelp, Wix, Auth0, Twilio, SendGrid, Zapier, and VeriSign are some notable investments made by this venture capital firm.

First Analysis

Location: Chicago

One of the leading venture capital investors in Chicago, First Analysis Venture Capital focuses primarily on three sectors – Environmental Technology, Healthcare, and SaaS/Technology.

This venture capital firm offers Seed and Series A investments, and the average check size is $3M to $10M. Apart from direct funding, this venture capital firm offers help to its portfolio companies in the form of strategy development, recruitment, marketing and sales, and corporate development.

So far, First Analysis Venture Capital has invested in 108 companies, some of which are PCMI, VIDA, Smart Commerce, Visage, 4G Clinical, and Lender Price, among others.

Norwest Venture Partners

Location: San Francisco, Palo Alto, India, Israel

Located in San Francisco, Palo Alto, Israel, and India, Norwest Venture Partners is a popular venture capital firm that offers Seed to Series A+ funding. This venture capital firm focuses on companies operating in the Consumer, Enterprise, and Healthcare sectors.

Norwest Venture Partners usually writes a check of anywhere between $1M and $30M. Apart from funds, the firm also offers mentoring and technical insights into building a successful company.

So far, this venture capital firm has invested in 444 companies, some of which are Udemy, Vector Solutions, Productiv, Opendoor, Imperfect Foods, Demandbase, Calm, Anomalo, Babylist, Amagi, and AbsenceSoft, among others.

Krillion Ventures

Location: Miami

Krillion Ventures is a venture capital firm located in Miami. It focuses on technology-driven startups trying to solve pressing problems in sectors such as real estate, financial services, and healthcare. The firm accepts both pre-revenue and revenue-generating startups. The pre-revenue startups must have a demonstrated proof of concept.

Krillion Ventures offers up to $1M in funding for Seed and Series A rounds. Apart from direct funding, they also provide ongoing support towards marketing, strategy, and further capital raising.

So far, this venture firm has invested in more than 20 companies with some notable names such as HomeLight, DeepBlocks, Cohealo, Wyre, Scoot, and Wheels Up among others.

Sandbox Industries

Location: Chicago

Sandbox Industries is a popular venture capital firm operational in Chicago. What is interesting is that they focus only on three segments – Healthcare, Insurance, and Sustainability, and the funding for each segment is taken care of by different wings/funds.

Though this venture capital firm keeps the exact investment amount undisclosed on its website, it does provide Seed to Series A+ funding. So far, Sandbox Industries has invested in 83 companies, some of which are Agrivida, Debut, Sound Agriculture, Nuritas, Rein, Prove, Gradient AI, Abacus Insights, Drips, Everly Health, HeartFlow, and Owl, among others.

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Menlo Ventures

Location: San Francisco, Menlo Park

Menlo Ventures is a popular venture capital firm located in San Francisco and Menlo Park. This venture capital firm offers Seed to Series A+ funding to companies operating in the Consumer, Healthcare, and Enterprise sectors. There is no mention of the exact investment amount anywhere on its website.

So far, Menlo Ventures has invested in 160 companies, some of which are Siri (acquired by Apple), Roku, Uber, Rover, HomeLight, Hotmail, Poshmark, Clarify, PillPack, Encoded Therapeutics, Particle, and Recursion.

This venture capital firm does not just invest money, but also offers valuable advice and insights to its portfolio companies to help them succeed and become sustainable businesses.

Fort Ventures

Location: Fort Worth

Fort Ventures is one of the most prominent venture capital firms located in Fort Worth. This venture capital firm does not disclose the exact investment amount anywhere on its website. However, it offers Seed and Series A investments to the selected companies.

This venture capital firm primarily targets companies in the tech, food, and biotech industries, and offers crucial guidance and support to its portfolio companies.

So far, Fort Ventures has invested in 35 companies, some of which are Thunkable, Eden, YSplit, MisappliedSciences, TripleByte, Chef’s Cut, Tilt, Backdrop, and Zego. Several of these companies have been acquired by other big companies.

Dreamit

Location: Philadelphia

Dreamit, which is one of Philadelphia’s famous VCs, works with startups in the HealthTech, SecureTech, and UrbanTech sectors. Dreamit offers seed-stage funding of up to $500k to eligible companies in return for some equity.

However, it is important to note that the companies who apply for Dreamit funding need to have revenue or pilot. Those that receive funding from the VC firm also receive access to a massive network of advisors. Additionally, they also receive hands-on training plus connections to potential customers.

So far, Dreamit has invested in over 300 companies some of which are big names like GoDaddy, American Express, Deloitte, etc.

Silverton Partners

Location: Austin

Located in Austin, Silverton Partners was founded in 2006. Ever since then, this venture capital firm has grown into one of the most active venture capital investors in entire Texas.

This venture capital firm offers Seed and Series A funding to companies in the Healthcare, Fintech, Enterprise, and Consumer verticals. Unfortunately, the firm does not disclose the exact investment amount anywhere on its website.

So far, Silverton Partners has invested in 80+ companies with some big names such as Stack Engine, WP Engine, Nuve, CopperEgg, Hive9, BigSquid.ai, Billie, Novo Labs, AlertMedia, SpyCloud, and Vacasa, among others.

Rho Ventures

Location: NYC

Based in NYC, Rho Ventures is one of the biggest and most prominent venture capital firms that offer Seed to Series A+ investments. Rho Ventures usually invests in companies that are operational in the Consumer, Healthcare, Enterprise, and Cleantech sectors.

The firm has so far invested in 243 companies, some of which include, Active Power, August, Answer Soft, Chango, CloudPay, Convercent, Dexai Robotics, Intra Links, and iVillage, among others.

Rho Ventures actively engages with its portfolio companies and offers necessary connections, networking opportunities, and mentorship to help them become successful businesses.

Keiretsu Capital

Location: Seattle

Keiretsu Capital is an exclusive and affiliate partner of Keiretsu Forum – a leading angel network in this world. Located in Seattle, this venture capital firm offers Seed investment to startups working in Impact, IT, Healthtech, Fintech, and Cleantech industries. Unfortunately, they do not disclose the exact investment amount.

Keiretsu Forum invests across the world and has 50+ chapters in Asia, Australia, Europe, and North America. Keiretsu Capital usually focuses on angel co-investment, and so far, they have invested in 120+ companies. 

Some of the many companies they have invested in include Astarte Medical Partners, Carmell Therapeutics, Forge Life Science, Alterna Card Services, RealKey, Phytonix Solar Chemicals, Building Energy, Clean Fiber, and more.

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