Spain’s Top 15 Venture Capital Firms [2022]

Spain has become one of Europe’s top destinations for tech startups. Indeed, Spain’s venture capital firms have invested in 2021 a total of €1.9 billion across 691 deals, a 248% increase vs. 2020.

In this article we have listed our top picks for Spain’s best venture capital firms. So, if you haven’t yet started to reach out, here is a good place to start learning about them.

This article is part of a series where we present you the top Venture Capital firms across the world. For Europe, check out our rankings for Amsterdam, Austria, Belgium, Berlin, Denmark, France, Ireland, Italy, Norway, Sweden, Switzerland and the UK.
Looking for Spain's top startup incubators and accelerators instead? Check out our ranking here.

Top 15 Venture Capital Firms In Spain

Here’s a summary of our top 15 picks for Spain’s best venture capital firms for tech startups (in alphabetical order):

NameSector focusRoundInvestment sizeInvestments
4Founders CapitalTechnologySeed, Series A, A+€100K-€4M33
Active Venture PartnersTechnologySeed, Series AUndisclosed42
Asabys PartnersHealthcare, Life SciencesSeedUndisclosed13
Axon Partners GroupTechnologySeries A+Undisclosed51
Bonsai Venture CapitalMobile Apps, Consumer TechSeed, Series A, A+€250K-€2.5M34
Caixa Capital RiscLife Sciences, TechnologySeed, Series A€500K-€4M250
Invivo CapitalLife SciencesSeed, Series A€500K-€2M11
JME CapitalTechnologySeed, Series AUndisclosed69
Lanta Digital VenturesSector AgnosticSeed, Series AUndisclosed8
Mundi VenturesTechnologySeries A, A+€500K-€5M72
Nauta CapitalTechnologySeed, Series A€1M-€5M133
SamaipataTechnologySeed, Series AUndisclosed40
Seaya VenturesTechnologySeedUndisclosed67
Seed Capital BizkaiaSector AgnosticSeed, Series A€450K- €1M20
Ysios CapitalLife SciencesSeed, Series A, A+Undisclosed59

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4Founders Capital

4Founders Capital is a venture capital firm seeking to collaborate with founders in building disruptive companies. Established by a group of serial entrepreneurs, the VC firm presents founders a solid experience and potential for building successful technology companies. In addition, the VC firm works with a vast network of famous internet entrepreneurs who co-invest and bring operational knowledge to assist the investee companies in scaling faster. 

To invest, 4Founders Capital looks for solid founding teams with a strong sense of business ownership and an international mindset. The VC firm looks for pre-seed and series A companies and invests from €400K to €4M. 

Active Venture Partners

Active Venture Partners is an investment company founded by entrepreneurs and seeks to help portfolio companies grow. The VC firm offers entrepreneurs access to world-class forums where the business founders can grow and learn from mentors. 

The venture builder provides the investee companies the tools they need to pin company vision and get the whole organization working towards a common goal. 

In addition, the VC firm helps entrepreneurs make the right decisions based on their goals. They apply their earned experience to ensure that portfolio companies perfect their strategy and maximize business growth. 

Asabys

Asabys Partners is a venture capital investment firm in Barcelona and invests in entrepreneurs that work towards building innovations to transform the healthcare and life science sectors. 

Typically, the VC firm seeks to push the boundaries of science and medicine to improve the patient’s life. 

Therefore, they look for highly innovative companies that work to create transformative technologies. To increase the chances of success, the VC firm ensures a hands-on approach and works with the management teams of their portfolio companies. 

Axon Partners Group

Axon Partners Group is an investment company that seeks to invest in the best entrepreneurs while delivering the best return to their investors. The venture builder supports in technology scale-ups and has preferences in the growth stages.

Typically, Axon Partners Group aims at generating value and combining excellence with entrepreneurship. In addition, their management teams possess strong technology expertise, enabling them to cover global opportunities while ensuring a multi-sector strategy.

The VC firm invests globally, and they have offices in Madrid, Medellin, Brussels, Medellin, Istanbul, Seville, and Riyadh. 

Bonsai Venture Capital

Bonsai Venture Capital is one of Spain’s best venture capital firms. It invests in domestic internet companies with great mobile focus and global ambition. The VC firm’s initial investments fall in the range of €250K and €2.5M per company, for an equity stage of between 10% and 25%.

The Vc firm invests in early and growth stages. They only target companies with a solid track record for seed capital investments.  Typically, Bonsai Venture Capital targets entrepreneurs who focus on mobile startups based on classifieds, e-health, games, payments, security, travel, and other high-growth sectors. 

Bonsai Venture Capital prefers working with entrepreneurs who have shown complete commitment to their ventures and are led by a solid team with solid management skills and good synergy with their Vc model.

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Caixa Capital Risc

Caixa Capital Risc is a venture capital firm that invests in innovative companies at the early and growth stages. The VC firm targets life sciences, industrial technologies, and information technology sectors. Since its inception, the VC firm has managed more than 200 Million Euros through 9 specialized vehicles and has made more than 250 investments.

For their investments in life sciences, the VC firm looks for companies that develop innovative therapies that address unmet medical needs and lead by committed management teams. The VC firm prefers leading or investing jointly for information and industrial technologies. 

The VC firm invests between €500K and €4M. 

Invivo Capital

Invivo Capital is undeniably one of Spain’s best venture capital firms. It invests in early-stage life science companies focusing on biotechnology, medical devices, and eHealth. The VC firm presents a team of highly qualified professionals with scientific, technical, and financial know-how to analyze and make investments that provide value and impact. Besides, the Vc firm links startups to a network of contacts and strategic partners who support business growth. 

The Venture builder seeks to support companies with powerful proof of concept and a solid scientific package. 

Invivo Capital sets an initial investment in the range of €500K and €2M and sets a milestone. Upon achieving the milestone, the investee company receives additional funding of up to €4M. 

JME Capital

JME Capital invests in early-stage startups and backs them to the exit stage. The VC firm provides their portfolio companies access to experienced experts and an extensive network of like-minded entrepreneurs. 

To help build excellent companies, they provide founders access to funding opportunities and operational support. The investment company partner’s with some of the best entrepreneurs and international investors.

Lanta Digital Ventures

Lanta Digital Ventures is a Venture capital firm that invests in innovative startups with high growth potential. 

The VC firm targets innovative companies with a global approach. They are committed to helping entrepreneurs who focus on solving an accepted problem with a clear and marketable solution. 

Typically, the investment firm looks for entrepreneurs with a transparent revenue model and massive scale potential seeking seed to early-stage funding.

Mundi Ventures

Mundi is a venture capital fund for technology-focused enterprises with B2B business models seeking funding for series A or series B stage

The VC firm invests between €500K and €5M per Portfolio Company. They have headquarters in Madrid and operational presence in Paris, Barcelona, Bilbao, New York, and London.

Mundi Ventures looks for entrepreneurs committed to developing differentiated products or patented technological solutions. They prefer investing in technologies that add value and transform the industry with an obsolete business model. 

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Nauta Capital

Nauta Capital is a venture investor backing founders who develop solutions that will challenge the status quo. The VC firm partners with the exceptional founders and teams from the seed stage to the Series A stages.

Investing in globally-minded founders across Europe, the VC firm prefers founders who venture into B2B SaaS solutions, enterprise technology, and deeptech applications to solve challenges faced by large enterprises. The Vc firm believes in partnering for the long haul and championing founders throughout their journey.

Nauta Capital’s initial investments fall in the range of €1 to €5M. since inception, they have backed over 60 companies, and they have assets worth over €550 Million under management.  

Samaipata

Samaipata is a venture capital firm investing in digital platforms. The VC firm prefers investments early and backs mission-driven entrepreneurs who strive to build the next unicorn. 

Samaipata invests in startups whose management believes in continuous learning and improvement. They support entrepreneurs who are relentless learners, who are unapologetically curious, and who want to create innovative solutions.

Samaipata supports their investee companies in sourcing, interviewing, and pitching talented staff. Besides, they connect the founders to a network of investors and strategic advisors in Madrid, Paris, London, and Lisbon.

Seaya Ventures

Seaya Ventures invests in exceptional founders committed to building leading technology companies. The Spanish Venture fund invests at the early and growth stages of technology companies operating in Spain and Latin America.

The investment firm seeks to transform the early and growth-stage companies by providing funding and enabling them to build lasting value.

Their investments focus mainly on the products and the services that facilitate the migration to a digital world. 

Bizkaia

Founded in 1989, Bizkaia is a venture investment firm on a mission to promote and develop newly created or existing companies. The VC firm targets the companies that seek to develop innovative and or socially innovative projects.

Seed Capital Bizkaia follows a general investee selection criteria, and each fund has its specific requirements. To receive funding or support from Seed Capital Bizkaia, the founders must have a registered office in Bizkaia. Besides, the promoter team must ensure financial involvement in the project they seek to raise funding for. 

Ysios Capital

Ysios Capital is a venture capital firm targeting founders within the life sciences sector. The VC firm aims to enable companies and startups that foster a positive impact on patients and society in general. Ysios Capital invests globally in biotech ventures and seeks exceptional teams with pioneering science and aiming at driving change.

They look for asset-centric companies and product enabling technology platforms with a proprietary pipeline. The VC firm seeks drug candidates with a solid scientific foundation backed by preclinical models or initial clinical data.

Ysios Capital takes an active role and supports the entrepreneurs by ensuring a hands-on involvement in the management’s daily operations. 

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